Detecting Past Positive Selection through Ongoing Negative Selection
نویسندگان
چکیده
منابع مشابه
Detecting Past Positive Selection through Ongoing Negative Selection
Detecting positive selection is a challenging task. We propose a method for detecting past positive selection through ongoing negative selection, based on comparison of the parameters of intraspecies polymorphism at functionally important and selectively neutral sites where a nucleotide substitution of the same kind occurred recently. Reduced occurrence of recently replaced ancestral alleles at...
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ژورنال
عنوان ژورنال: Genome Biology and Evolution
سال: 2011
ISSN: 1759-6653
DOI: 10.1093/gbe/evr086